Friday, March 23, 2007

Rituxan/Cytoxan -- round three

Hi everyone:

Patty completed her third round of Rituxan/Cytoxan this afternoon; as usual, she slept for much of the time, and is home and doing pretty well right now. Before the infusion, Patty's blood was drawn, and we packed it up and mailed it before noon. With luck, we'll get the PRA results earlier this time (late next week, perhaps); with some real luck, perhaps the numbers will be much more encouraging. I still find it astounding that a PRA of 20% is considered high, when Patty's is at 100%.

Can one or more of the statisticians in the family figure out what the odds are against a successful match if on one front Patty is incompatible with 60 of 100 prospects, and on another she's a no-go with 100 of 100, and both fronts are near-absolute factors against a transplant? For example, I know that if the second number was 90 out of 100, the incompatible group would be greater than 90 percent, because of the other PRA factor of 60/100. I guess I'm just trying to grasp what might ultimately seem like a hopeful set of numbers. I know that 0%/0% would be a nice goal.

As you can see from the photo, Patty started the day feeling energetic and in good spirits. She seems to be in a similar state now, after a day of deep napping. I don't want to sound too pessimistic, but I suspect Patty will be in a different condition over the next couple of days, once the meds start to kick in. Have a great weekend, everyone.


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